Contraceptive pill for MEN is a step closer after Australian discovery

Why MEN may quickly be taking a contraceptive tablet – as Australian scientists make a breakthrough discovery that may lastly make it secure to make use of

  • Monash College found a leaf extract which will hinder sperm motion
  • The stinging nettle extract has diminished fertility by 53 per cent in male mice
  •  The analysis group is working to develop a hormone-free male contraceptive
  • ‘There was a widespread notion contraception is a girls’s drawback’ 

A male contraceptive tablet might be a step nearer to turning into a actuality, with Australian researchers discovering a leaf extract has the potential to hinder sperm motion.

In a peer-reviewed examine revealed in journal PLOS ONE, the analysis crew from Melbourne‘s Monash College examined the pharmacological impact of a stinging nettle leaf extract on mice.

An extract of the stinging nettle leaf (picture) has been shown to reduce male fertility in mice

An extract of the stinging nettle leaf (image) has been proven to scale back male fertility in mice

Monash University researchers are working to develop a hormone-free contraceptive for men

Monash College researchers are working to develop a hormone-free contraceptive for males

They discovered it could inhibit P2X1-purinoceptor, one in all two proteins that set off the transport of sperm.

‘In mouse mating research, stinging nettle leaf extract diminished male fertility by 53 per cent in comparison with vehicle-treated male mice,’ reads the examine, led by Dr Sab Ventura from the Monash Institute of Pharmaceutical Science.

‘Handled mice exhibited regular mating behaviour. Bladder and testes weighed much less in stinging nettle leaf extract handled mice. All different organs and whole physique weight had been unaffected.’

Dr Ventura’s analysis group is working to develop a hormone-free male contraceptive and has beforehand proven male infertility could be genetically achieved with out affecting long-term sperm viability or sexual and common well being.

The burden of birth control has been placed on women, with condoms and vasectomy the only alternative for men

The burden of contraception has been positioned on girls, with condoms and vasectomy the one various for males

The consequence signifies the crew’s mechanism for male contraception is orally viable, with the subsequent step to isolate the bioactive element within the extract or establish an analogous various compound.

‘As soon as remoted and recognized, this will have potential as a drug-like lead compound,’ the examine says.

Condoms and vasectomy stay the one publicly obtainable types of contraception for males in Australia, putting the burden for stopping being pregnant largely and erratically on girls.

‘Sadly there was a widespread notion that contraception is a girls’s drawback relatively than a males’s drawback,’ Dr Ventura mentioned.

‘Nonetheless, analysis led by the Male Contraceptive Initiative reveals that almost all of males are keen to take management over contraception – we simply want to present them the chance to take action.’


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